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KMID : 0032220210330040361
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Annals of Dermatology
2021 Volume.33 No. 4 p.361 ~ p.364
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Extensive Nevus Comedonicus with Inflammatory Nodules and Cysts Controlled with Adalimumab
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Lee Eun-Hye
Lee Seon-Hwa
Sohng Chi-Hyeon
Kim Jun-Young
Park Kyung-Duck
Lee Seok-Jong
Lee Weon-Ju
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Abstract
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Nevus comedonicus is a very rare skin disorder characterized by the presence of comedo-like dilated pores with keratinous plugs, rarely resulting in painful recurrent inflammatory nodules or cysts. It presents as localized or extensive form. It displays unilaterally or bilaterally segmental distribution. Histopathologically, it is characterized by keratin-filled epidermal invagination with bulbous proliferation of keratinocytes. The condition may be caused by fibroblast growth factor receptor 2 mutation. Although it may be controlled by a variety of therapeutic modalities, it is difficult to achieve complete resolution. We report a case of extensive nevus comedonicus with inflammatory nodules and cysts controlled with adalimumab.
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KEYWORD
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Adalimumab, Extensive nevus comedonicus
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